IPR041091
RPGRIP1, C-terminal
InterPro entry
Short name | RPGRIP1_C |
Overlapping homologous superfamilies |
Description
This is the C-terminal domain of retinitis pigmentosa G-protein regulator (RPGR) interacting protein-1 (RPGRIP1) present in Homo sapiens. A mutation in RPGRIP1 can be observed in the eye disease Leber congenital amaurosis. The domain is commonly known as the RPGR-interacting domain (RID) and is thought to have a C2-like fold
[1].
References
1.C2 domains as protein-protein interaction modules in the ciliary transition zone. Remans K, Burger M, Vetter IR, Wittinghofer A. Cell Rep 8, 1-9, (2014). View articlePMID: 24981858
Contributing Member Database Entry
- Pfam:PF18111