D
IPR041091

RPGRIP1, C-terminal

InterPro entry
Short nameRPGRIP1_C
Overlapping
homologous
superfamilies
 

Description

This is the C-terminal domain of retinitis pigmentosa G-protein regulator (RPGR) interacting protein-1 (RPGRIP1) present in Homo sapiens. A mutation in RPGRIP1 can be observed in the eye disease Leber congenital amaurosis. The domain is commonly known as the RPGR-interacting domain (RID) and is thought to have a C2-like fold
[1]
.

References

1.C2 domains as protein-protein interaction modules in the ciliary transition zone. Remans K, Burger M, Vetter IR, Wittinghofer A. Cell Rep 8, 1-9, (2014). View articlePMID: 24981858

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