D
IPR041559

DNA ligase, ATP-dependent, bacteriophage T7-type, C-terminal

InterPro entry
Short nameDNA_ligase_ATP-dep_T7_C
Overlapping
homologous
superfamilies
 

Description

This is the C-terminal domain found in ATP-Dependent DNA ligase from Bacteriophage T7. This domain has no ligase activity, however together with the N-terminal domain (domain 1) they bind to double-stranded DNA consistent with the idea that the DNA-binding site is between the domains in the intact protein. While the fold of domain 2 (this domain) is very similar to a number of other proteins that bind single-stranded DNA, this domain does not bind to single-stranded DNA but instead has a high affinity for double-stranded DNA
[1]
.

References

1.Crystal structure of an ATP-dependent DNA ligase from bacteriophage T7. Subramanya HS, Doherty AJ, Ashford SR, Wigley DB. Cell 85, 607-15, (1996). View articlePMID: 8653795

GO terms

biological process

  • None

cellular component

  • None

Cross References

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