IPR043129
ATPase, nucleotide binding domain
InterPro entry
Short name | ATPase_NBD |
Overlapping entries |
Description
This superfamily comprises domains found in several ATPases, including actin, Hsp70, BadF/BadG/BcrA/BcrD, various kinases, DnaK, ROK, PilM, and Fumble. Members of this superfamily have two lobes, one with nucleotide binding activity, and a second one with substrate binding activity. The lobes can be structurally divided into 4 subdomains - 1A, 1B, 2A, 2B (or 1, 2, 3, 4). The ATP binding site in these ATPases is well conserved, and is located at the junction of the two lobes, in a deep cleft. This superfamily entry represents the nucleotide binding domain (NBD) or the first lobe (subdomains 1A and 1B), which exhibits ATPase activity.
Cross References
ENZYME
- 1.3.7.8
- 2.1.3.-
- 2.1.3.12
- 2.3.1.234
- 2.5.1.131
- 2.7.1.-
- 2.7.1.1
- 2.7.1.12
- 2.7.1.14
- 2.7.1.16
- 2.7.1.17
- 2.7.1.170
- 2.7.1.179
- 2.7.1.188
- 2.7.1.189
- 2.7.1.2
- 2.7.1.214
- 2.7.1.215
- 2.7.1.232
- 2.7.1.233
- 2.7.1.30
- 2.7.1.33
- 2.7.1.4
- 2.7.1.45
- 2.7.1.47
- 2.7.1.5
- 2.7.1.51
- 2.7.1.53
- 2.7.1.55
- 2.7.1.58
- 2.7.1.59
- 2.7.1.60
- 2.7.1.63
- 2.7.1.8
- 2.7.1.85
- 2.7.10.2
- 2.7.11.1
- 2.7.11.32
- 2.7.2.1
- 2.7.2.15
- 2.7.2.7
- 2.7.4.1
- 2.7.4.27
- 3.1.3.-
- 3.2.1.183
- 3.5.2.-
- 3.6.1.-
- 3.6.1.11
- 3.6.1.40
- 3.6.4.-
- 3.6.4.10
- 4.2.3.4
- 5.1.3.9
- 5.3.1.14
- 6.1.2.2
- 6.3.4.15
- 6.4.1.6
Contributing Member Database Entry
- SUPERFAMILY:SSF53067
Representative structure
5zza: OdinProfilin/Rabbit Actin Complex