Nonstructural protein 15, middle domain, coronavirus
Short name | CoV_NSP15_M |
Overlapping homologous superfamilies | |
domain relationships |
Description
References
1.Crystal structure of Nsp15 endoribonuclease NendoU from SARS-CoV-2. Kim Y, Jedrzejczak R, Maltseva NI, Wilamowski M, Endres M, Godzik A, Michalska K, Joachimiak A. Protein Sci. (2020). PMID: 32304108
2.Cryo-EM structures of the SARS-CoV-2 endoribonuclease Nsp15 reveal insight into nuclease specificity and dynamics. Pillon MC, Frazier MN, Dillard LB, Williams JG, Kocaman S, Krahn JM, Perera L, Hayne CK, Gordon J, Stewart ZD, Sobhany M, Deterding LJ, Hsu AL, Dandey VP, Borgnia MJ, Stanley RE. Nat Commun 12, 636, (2021). PMID: 33504779
3.Biochemical characterization of arterivirus nonstructural protein 11 reveals the nidovirus-wide conservation of a replicative endoribonuclease. Nedialkova DD, Ulferts R, van den Born E, Lauber C, Gorbalenya AE, Ziebuhr J, Snijder EJ. J. Virol. 83, 5671-82, (2009). PMID: 19297500
4.An "Old" protein with a new story: Coronavirus endoribonuclease is important for evading host antiviral defenses. Deng X, Baker SC. Virology 517, 157-163, (2018). PMID: 29307596
5.New antiviral target revealed by the hexameric structure of mouse hepatitis virus nonstructural protein nsp15. Xu X, Zhai Y, Sun F, Lou Z, Su D, Xu Y, Zhang R, Joachimiak A, Zhang XC, Bartlam M, Rao Z. J. Virol. 80, 7909-17, (2006). View articlePMID: 16873248
Cross References
Contributing Member Database Entry
- Pfam:PF19216