F
IPR044292

Regulatory protein NPR

InterPro entry
Short nameNPR

Description

This entry represents a group of plant regulatory proteins, including NPR1-4 from Arabidopsis. NPR1 is a central regulator of salicylic-acid (SA)-mediated defense signaling in Arabidopsis. It contains a BTB/POZ domain at the N-terminal and an ankyrin-repeat domain in the central region. It binds to TGA1, a member of the TGA family of transcription factors that activate SA-responsive elements in the promoters of PR (PATHOGENESIS-RELATED) genes. It also has cytosolic function in cross-communication between SA- and JA-dependent defense signaling pathways
[4]
. NPR1 is functionally conserved in diverse plant species, including rice (Oryza sativa L.)
[3]
. NPR3 and NPR4 have also been shown to be required for basal defense against pathogens
[1, 2]
.

References

1.An Arabidopsis NPR1-like gene, NPR4, is required for disease resistance. Liu G, Holub EB, Alonso JM, Ecker JR, Fobert PR. Plant J 41, 304-18, (2005). PMID: 15634206

2.Negative regulation of defense responses in Arabidopsis by two NPR1 paralogs. Zhang Y, Cheng YT, Qu N, Zhao Q, Bi D, Li X. Plant J 48, 647-56, (2006). PMID: 17076807

3.Functional analysis of rice NPR1-like genes reveals that OsNPR1/NH1 is the rice orthologue conferring disease resistance with enhanced herbivore susceptibility. Yuan Y, Zhong S, Li Q, Zhu Z, Lou Y, Wang L, Wang J, Wang M, Li Q, Yang D, He Z. Plant Biotechnol J 5, 313-24, (2007). PMID: 17309686

4.NPR1: the spider in the web of induced resistance signaling pathways. Pieterse CM, Van Loon LC. Curr Opin Plant Biol 7, 456-64, (2004). PMID: 15231270

GO terms

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