Mastermind-like 1-3
Short name | MAML1-3 |
Overlapping homologous superfamilies |
Description
References
1.Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes. Nam Y, Sliz P, Song L, Aster JC, Blacklow SC. Cell 124, 973-83, (2006). View articlePMID: 16530044
2.More complicated than it looks: assembly of Notch pathway transcription complexes. Kovall RA. Oncogene 27, 5099-109, (2008). View articlePMID: 18758478
3.Mastermind-like transcriptional co-activators: emerging roles in regulating cross talk among multiple signaling pathways. McElhinny AS, Li JL, Wu L. Oncogene 27, 5138-47, (2008). View articlePMID: 18758483
4.The Notch coactivator, MAML1, functions as a novel coactivator for MEF2C-mediated transcription and is required for normal myogenesis. Shen H, McElhinny AS, Cao Y, Gao P, Liu J, Bronson R, Griffin JD, Wu L. Genes Dev. 20, 675-88, (2006). View articlePMID: 16510869
5.The notch regulator MAML1 interacts with p53 and functions as a coactivator. Zhao Y, Katzman RB, Delmolino LM, Bhat I, Zhang Y, Gurumurthy CB, Germaniuk-Kurowska A, Reddi HV, Solomon A, Zeng MS, Kung A, Ma H, Gao Q, Dimri G, Stanculescu A, Miele L, Wu L, Griffin JD, Wazer DE, Band H, Band V. J. Biol. Chem. 282, 11969-81, (2007). View articlePMID: 17317671
6.Mastermind-like 1 Is a specific coactivator of beta-catenin transcription activation and is essential for colon carcinoma cell survival. Alves-Guerra MC, Ronchini C, Capobianco AJ. Cancer Res. 67, 8690-8, (2007). View articlePMID: 17875709
7.Identification of a conserved negative regulatory sequence that influences the leukemogenic activity of NOTCH1. Chiang MY, Xu ML, Histen G, Shestova O, Roy M, Nam Y, Blacklow SC, Sacks DB, Pear WS, Aster JC. Mol. Cell. Biol. 26, 6261-71, (2006). View articlePMID: 16880534
8.The transcriptional coactivator Maml1 is required for Notch2-mediated marginal zone B-cell development. Wu L, Maillard I, Nakamura M, Pear WS, Griffin JD. Blood 110, 3618-23, (2007). View articlePMID: 17699740
9.NOTCH3 expression is induced in mural cells through an autoregulatory loop that requires endothelial-expressed JAGGED1. Liu H, Kennard S, Lilly B. Circ. Res. 104, 466-75, (2009). PMID: 19150886
10.Transforming activity of MECT1-MAML2 fusion oncoprotein is mediated by constitutive CREB activation. Wu L, Liu J, Gao P, Nakamura M, Cao Y, Shen H, Griffin JD. EMBO J. 24, 2391-402, (2005). View articlePMID: 15961999
11.Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover. Fryer CJ, White JB, Jones KA. Mol. Cell 16, 509-20, (2004). View articlePMID: 15546612
GO terms
molecular function
cellular component
- None
Contributing Member Database Entry
- PANTHER:PTHR15692