Fatty acid synthase, pseudo-KR domain
Short name | FAS_pseudo-KR |
Description
References
1.The crystal structure of a mammalian fatty acid synthase. Maier T, Leibundgut M, Ban N. Science 321, 1315-22, (2008). View articlePMID: 18772430
2.Discovery and optimization of novel piperazines as potent inhibitors of fatty acid synthase (FASN). Martin MW, Lancia DR Jr, Li H, Schiller SER, Toms AV, Wang Z, Bair KW, Castro J, Fessler S, Gotur D, Hubbs SE, Kauffman GS, Kershaw M, Luke GP, McKinnon C, Yao L, Lu W, Millan DS. Bioorg Med Chem Lett 29, 1001-1006, (2019). PMID: 30803804
3.A human fatty acid synthase inhibitor binds β-ketoacyl reductase in the keto-substrate site. Hardwicke MA, Rendina AR, Williams SP, Moore ML, Wang L, Krueger JA, Plant RN, Totoritis RD, Zhang G, Briand J, Burkhart WA, Brown KK, Parrish CA. Nat Chem Biol 10, 774-9, (2014). View articlePMID: 25086508
Cross References
Contributing Member Database Entry
- Pfam:PF21149