IPR050832
Bacterial Acetyltransferase AI
InterPro entry
This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Short name | Bact_Acetyltransf AI |
Overlapping homologous superfamilies |
Description
AI-generatedUnreviewed
The acetyltransferase family encompasses enzymes that catalyze the transfer of acetyl groups from acetyl-CoA to various substrates, conferring specific functions such as antibiotic resistance or metabolic regulation. Members of this family are involved in resistance mechanisms against aminoglycoside antibiotics by acetylating the 6'-amino group of the molecules, thus inactivating the drugs. Other family members acetylate mycothiol, a compound that acts as an antioxidant in certain bacteria, or are involved in the biosynthesis of bacterial cell components such as the enterobacterial common antigen. Some enzymes within this family also participate in phytohormone production or detoxification processes. The diversity of substrates and reactions highlights the family's role in bacterial survival and adaptation.
Cross References
Contributing Member Database Entry
- PANTHER:PTHR43877
Representative structure
1z4e: Crystal structure of transcriptional regulator from Bacillus halodurans C-125