Fibronectin type III domain-containing protein 4/5
Short name | FNDC_type_III_4/5 |
Description
References
1.A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. Bostrom P, Wu J, Jedrychowski MP, Korde A, Ye L, Lo JC, Rasbach KA, Bostrom EA, Choi JH, Long JZ, Kajimura S, Zingaretti MC, Vind BF, Tu H, Cinti S, Hojlund K, Gygi SP, Spiegelman BM. Nature 481, 463-8, (2012). View articlePMID: 22237023
2.Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors. Kim H, Wrann CD, Jedrychowski M, Vidoni S, Kitase Y, Nagano K, Zhou C, Chou J, Parkman VA, Novick SJ, Strutzenberg TS, Pascal BD, Le PT, Brooks DJ, Roche AM, Gerber KK, Mattheis L, Chen W, Tu H, Bouxsein ML, Griffin PR, Baron R, Rosen CJ, Bonewald LF, Spiegelman BM. Cell 175, 1756-1768.e17, (2018). View articlePMID: 30550785
3.FNDC4 acts as an anti-inflammatory factor on macrophages and improves colitis in mice. Bosma M, Gerling M, Pasto J, Georgiadi A, Graham E, Shilkova O, Iwata Y, Almer S, Soderman J, Toftgard R, Wermeling F, Bostrom EA, Bostrom PA. Nat Commun 7, 11314, (2016). View articlePMID: 27066907
4.Evidence against a beneficial effect of irisin in humans. Raschke S, Elsen M, Gassenhuber H, Sommerfeld M, Schwahn U, Brockmann B, Jung R, Wisloff U, Tjonna AE, Raastad T, Hallen J, Norheim F, Drevon CA, Romacho T, Eckardt K, Eckel J. PLoS One 8, e73680, (2013). View articlePMID: 24040023
Contributing Member Database Entry
- PANTHER:PTHR14470