IPR052379
Type VII TA system RNase AI
InterPro entry
This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Short name | Type_VII_TA_RNase AI |
Overlapping homologous superfamilies |
Description
AI-generatedUnreviewed
This family of proteins includes RNases that are typically components of type VII toxin-antitoxin (TA) systems. These RNases are usually toxic when expressed alone, inhibiting cell growth by cleaving RNA molecules such as tRNA or mRNA, depending on the member. The toxicity is counteracted by cognate antitoxins, which neutralize the RNase activity through various modifications such as AMPylation. These systems are thought to play a role in maintaining plasmid stability and may be involved in bacterial stress responses or competition.
Cross References
ENZYME
Contributing Member Database Entry
- PANTHER:PTHR33397
Representative structure
1ylm: Structure of Cytosolic Protein of Unknown Function YutE from Bacillus subtilis