F
IPR052379

Type VII TA system RNase
AI

InterPro entry
This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Short nameType_VII_TA_RNase
AI
Overlapping
homologous
superfamilies
 

Description

AI-generatedUnreviewed
This family of proteins includes RNases that are typically components of type VII toxin-antitoxin (TA) systems. These RNases are usually toxic when expressed alone, inhibiting cell growth by cleaving RNA molecules such as tRNA or mRNA, depending on the member. The toxicity is counteracted by cognate antitoxins, which neutralize the RNase activity through various modifications such as AMPylation. These systems are thought to play a role in maintaining plasmid stability and may be involved in bacterial stress responses or competition.

Cross References

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