D
IPR054065

Baseplate wedge protein gp6, C-terminal domain III

InterPro entry
Short nameGp6_C-III

Description

This entry represents a domain found in Baseplate wedge protein gp6 from Enterobacteria phage T4 (Gp6) and similar sequences from tailed bacteriophages and bacterial prophages. Gp6 is located next to the tail tube and is an intermediate (or inner) baseplate protein involved in tail assembly. Two molecules of Gp6 form a complex with Gp25 and Gp7, which is involved sheath contraction
[3, 1, 2]
. This domain has been described as C-terminal domain III.

References

1.Role of bacteriophage T4 baseplate in regulating assembly and infection. Yap ML, Klose T, Arisaka F, Speir JA, Veesler D, Fokine A, Rossmann MG. Proc Natl Acad Sci U S A 113, 2654-9, (2016). PMID: 26929357

2.Structure of the T4 baseplate and its function in triggering sheath contraction. Taylor NM, Prokhorov NS, Guerrero-Ferreira RC, Shneider MM, Browning C, Goldie KN, Stahlberg H, Leiman PG. Nature 533, 346-52, (2016). View articlePMID: 27193680

3.The structure of gene product 6 of bacteriophage T4, the hinge-pin of the baseplate. Aksyuk AA, Leiman PG, Shneider MM, Mesyanzhinov VV, Rossmann MG. Structure 17, 800-8, (2009). View articlePMID: 19523898

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