G3DSA:1.10.1220.10

Met repressor-like

CATH-Gene3D entry
Member databaseCATH-Gene3D
CATH-Gene3D typehomologous superfamily

Description
Imported from IPR013321

This superfamily represents a domain with a ribbon-helix-helix topology consisting of four helices in an open array of two hairpins. This domain is found in Mnt and Arc, two structurally homologous repressors encoded by bacteriophage P22
[1, 2]
. This entry also includes nickel-responsive regulator
[3]
and protein CopG
[4]
.

References
Imported from IPR013321

1.Solution structure of dimeric Mnt repressor (1-76). Burgering MJ, Boelens R, Gilbert DE, Breg JN, Knight KL, Sauer RT, Kaptein R. Biochemistry 33, 15036-45, (1994). View articlePMID: 7999761

2.Role of an N(cap) residue in determining the stability and operator-binding affinity of Arc repressor. Anderson TA, Sauer RT. Biophys. Chem. 100, 341-50, (2003). View articlePMID: 12646376

3.NikR-operator complex structure and the mechanism of repressor activation by metal ions. Schreiter ER, Wang SC, Zamble DB, Drennan CL. Proc. Natl. Acad. Sci. U.S.A. 103, 13676-81, (2006). View articlePMID: 16945905

4.The structure of plasmid-encoded transcriptional repressor CopG unliganded and bound to its operator. Gomis-Ruth FX, Sola M, Acebo P, Parraga A, Guasch A, Eritja R, Gonzalez A, Espinosa M, del Solar G, Coll M. EMBO J. 17, 7404-15, (1998). View articlePMID: 9857196

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