Member database | CATH-Gene3D |
CATH-Gene3D type | homologous superfamily |
Description Imported from IPR042097
Aminopeptidase N from Escherichia coli is a broad specificity zinc exopeptidase belonging to aminopeptidase clan MA, family M1. The enzyme is composed of four domains: an N-terminal beta-domain, a catalytic domain, a middle beta-domain and a C-terminal alpha-domain
[1].
This superfamily represents the N-terminal domain found in aminopeptidases and related proteins.
References Imported from IPR042097
1.Crystal structure of aminopeptidase N (proteobacteria alanyl aminopeptidase) from Escherichia coli and conformational change of methionine 260 involved in substrate recognition. Ito K, Nakajima Y, Onohara Y, Takeo M, Nakashima K, Matsubara F, Ito T, Yoshimoto T. J. Biol. Chem. 281, 33664-76, (2006). View articlePMID: 16885166