Member database | CATH-Gene3D |
CATH-Gene3D type | homologous superfamily |
Description Imported from IPR027478
This superfamily represents the N-terminal of muramoyl-tetrapeptide carboxypeptidase, also known as LD-carboxypeptidase A. The enzyme hydrolyses a peptide bond between a di-basic amino acid and the C-terminal D-alanine in the tetrapeptide moiety in peptidoglycan. This cleaves the bond between an L- and a D-amino acid. This activity is has a role ine in murein recycling
[2, 1]. Proteins containing this domain also include the microcin c7 self-immunity protein
Q47511.
References Imported from IPR027478
1.How bacteria consume their own exoskeletons (turnover and recycling of cell wall peptidoglycan). Park JT, Uehara T. Microbiol. Mol. Biol. Rev. 72, 211-27, table of contents, (2008). View articlePMID: 18535144
2.A defect in cell wall recycling triggers autolysis during the stationary growth phase of Escherichia coli. Templin MF, Ursinus A, Holtje JV. EMBO J. 18, 4108-17, (1999). View articlePMID: 10428950