Member database | CATH-Gene3D |
CATH-Gene3D type | homologous superfamily |
Description Imported from IPR036635
This entry represents a C-terminal conserved region of UDP-N-acetylenolpyruvoylglucosamine reductase
1.1.1.158, which is also called UDP-N-acetylmuramate dehydrogenase. The C-terminal domain is involved in substrate binding
[1]. It is a part of the pathway for the biosynthesis of the UDP-N-acetylmuramoyl-pentapeptide, which is a precursor of bacterial peptidoglycan.
References Imported from IPR036635
1.(E)-enolbutyryl-UDP-N-acetylglucosamine as a mechanistic probe of UDP-N-acetylenolpyruvylglucosamine reductase (MurB). Lees WJ, Benson TE, Hogle JM, Walsh CT. Biochemistry 35, 1342-51, (1996). View articlePMID: 8634262