G3DSA:3.90.78.10

UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain

CATH-Gene3D entry
Member databaseCATH-Gene3D
CATH-Gene3D typehomologous superfamily

Description
Imported from IPR036635

This entry represents a C-terminal conserved region of UDP-N-acetylenolpyruvoylglucosamine reductase
1.1.1.158
, which is also called UDP-N-acetylmuramate dehydrogenase. The C-terminal domain is involved in substrate binding
[1]
. It is a part of the pathway for the biosynthesis of the UDP-N-acetylmuramoyl-pentapeptide, which is a precursor of bacterial peptidoglycan.

References
Imported from IPR036635

1.(E)-enolbutyryl-UDP-N-acetylglucosamine as a mechanistic probe of UDP-N-acetylenolpyruvylglucosamine reductase (MurB). Lees WJ, Benson TE, Hogle JM, Walsh CT. Biochemistry 35, 1342-51, (1996). View articlePMID: 8634262

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