Member database | CDD |
CDD type | domain |
Short name | AP2Ec |
Set | AP2Ec |
Description
AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of D-arabino-6-hexulose 3-phosphate to D-fructose 6-phosphate, via cleaving the phosphoesterbond with the sugar.
[1]References
Integrated to
External Links
Representative structure
3aam: Crystal structure of endonuclease IV from Thermus thermophilus HB8