cd00412

pyrophosphatase

CDD entry
Member databaseCDD
CDD typedomain
Short namepyrophosphatase
Setpyrophosphatase

Description

Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers.
[3, 4, 1, 2]

References

1.Evolutionary conservation of the active site of soluble inorganic pyrophosphatase. Cooperman BS, Baykov AA, Lahti R. Trends Biochem. Sci. 17, 262-6, (1992). View articlePMID: 1323891

2.Microbial inorganic pyrophosphatases. Lahti R. Microbiol Rev 47, 169-78, (1983). PMID: 6135978

3.Active site interactions in oligomeric structures of inorganic pyrophosphatases. Avaeva SM. Biochemistry Mosc. 65, 361-72, (2000). PMID: 10739480

4.Inorganic polyphosphate: a molecule of many functions. Kornberg A. Prog. Mol. Subcell. Biol. 23, 1-18, (1999). PMID: 10448669

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