Member database | CDD |
CDD type | domain |
Short name | Bacterial_PFK |
Set | PFK |
Description
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent phosphofructokinases. These are allosrterically regulated homotetramers; the subunits are of about 320 amino acids.
[1]References
1.The biochemical properties and phylogenies of phosphofructokinases from extremophiles. Ronimus RS, Morgan HW. Extremophiles 5, 357-73, (2001). View articlePMID: 11778837
Integrated to
External Links
Representative structure
1zxx: The crystal structure of phosphofructokinase from Lactobacillus delbrueckii