Member database | CDD |
CDD type | domain |
Short name | FERM_F1_SNX27 |
Set | Ubl1_cv_Nsp3_N-like |
Description
References
1.Phosphoinositide binding by the SNX27 FERM domain regulates its localization at the immune synapse of activated T-cells. Ghai R, Tello-Lafoz M, Norwood SJ, Yang Z, Clairfeuille T, Teasdale RD, Merida I, Collins BM. J. Cell. Sci. 128, 553-65, (2015). View articlePMID: 25472716
2.New sorting nexin (SNX27) and NHERF specifically interact with the 5-HT4a receptor splice variant: roles in receptor targeting. Joubert L, Hanson B, Barthet G, Sebben M, Claeysen S, Hong W, Marin P, Dumuis A, Bockaert J. J Cell Sci 117, 5367-79, (2004). PMID: 15466885
3.PX-FERM proteins: A link between endosomal trafficking and signaling? Ghai R, Collins BM. Small GTPases 2, 259-263, (2011). View articlePMID: 22292128
4.Polarization of endosomal SNX27 in migrating and tumor-engaged natural killer cells. MacNeil AJ, Pohajdak B. Biochem Biophys Res Commun 361, 146-50, (2007). PMID: 17644068
5.A molecular code for endosomal recycling of phosphorylated cargos by the SNX27-retromer complex. Clairfeuille T, Mas C, Chan AS, Yang Z, Tello-Lafoz M, Chandra M, Widagdo J, Kerr MC, Paul B, Merida I, Teasdale RD, Pavlos NJ, Anggono V, Collins BM. Nat Struct Mol Biol 23, 921-932, (2016). PMID: 27595347
6.Interaction of the Human Papillomavirus E6 Oncoprotein with Sorting Nexin 27 Modulates Endocytic Cargo Transport Pathways. Ganti K, Massimi P, Manzo-Merino J, Tomaic V, Pim D, Playford MP, Lizano M, Roberts S, Kranjec C, Doorbar J, Banks L. PLoS Pathog 12, e1005854, (2016). PMID: 27649450
7.SNX27, a protein involved in down syndrome, regulates GPR17 trafficking and oligodendrocyte differentiation. Meraviglia V, Ulivi AF, Boccazzi M, Valenza F, Fratangeli A, Passafaro M, Lecca D, Stagni F, Giacomini A, Bartesaghi R, Abbracchio MP, Ceruti S, Rosa P. Glia 64, 1437-60, (2016). PMID: 27270750
8.Sorting nexin 27 interacts with multidrug resistance-associated protein 4 (MRP4) and mediates internalization of MRP4. Hayashi H, Naoi S, Nakagawa T, Nishikawa T, Fukuda H, Imajoh-Ohmi S, Kondo A, Kubo K, Yabuki T, Hattori A, Hirouchi M, Sugiyama Y. J Biol Chem 287, 15054-65, (2012). PMID: 22411990
9.Insights into the PX (phox-homology) domain and SNX (sorting nexin) protein families: structures, functions and roles in disease. Teasdale RD, Collins BM. Biochem. J. 441, 39-59, (2012). View articlePMID: 22168438
10.Translocation dynamics of sorting nexin 27 in activated T cells. Rincon E, Saez de Guinoa J, Gharbi SI, Sorzano CO, Carrasco YR, Merida I. J Cell Sci 124, 776-88, (2011). PMID: 21303929
11.Actin-Sorting Nexin 27 (SNX27)-Retromer Complex Mediates Rapid Parathyroid Hormone Receptor Recycling. McGarvey JC, Xiao K, Bowman SL, Mamonova T, Zhang Q, Bisello A, Sneddon WB, Ardura JA, Jean-Alphonse F, Vilardaga JP, Puthenveedu MA, Friedman PA. J Biol Chem 291, 10986-1002, (2016). PMID: 27008860
12.A role for novel lipid interactions in the dynamic recruitment of SNX27 to the T-cell immune synapse. Tello-Lafoz M, Ghai R, Collins B, Merida I. Bioarchitecture 4, 215-20, (2014). PMID: 25996807
13.Sorting nexin 27 couples PTHR trafficking to retromer for signal regulation in osteoblasts during bone growth. Chan AS, Clairfeuille T, Landao-Bassonga E, Kinna G, Ng PY, Loo LS, Cheng TS, Zheng M, Hong W, Teasdale RD, Collins BM, Pavlos NJ. Mol Biol Cell 27, 1367-82, (2016). PMID: 26912788
14.FAM21 directs SNX27-retromer cargoes to the plasma membrane by preventing transport to the Golgi apparatus. Lee S, Chang J, Blackstone C. Nat Commun 7, 10939, (2016). PMID: 26956659
15.Sorting nexin 27 (SNX27) associates with zonula occludens-2 (ZO-2) and modulates the epithelial tight junction. Zimmerman SP, Hueschen CL, Malide D, Milgram SL, Playford MP. Biochem J 455, 95-106, (2013). PMID: 23826934
16.Sorting nexin 27 regulates Aβ production through modulating γ-secretase activity. Wang X, Huang T, Zhao Y, Zheng Q, Thompson RC, Bu G, Zhang YW, Hong W, Xu H. Cell Rep 9, 1023-33, (2014). PMID: 25437557
17.Proteomics identification of sorting nexin 27 as a diacylglycerol kinase zeta-associated protein: new diacylglycerol kinase roles in endocytic recycling. Rincon E, Santos T, Avila-Flores A, Albar JP, Lalioti V, Lei C, Hong W, Merida I. Mol Cell Proteomics 6, 1073-87, (2007). PMID: 17351151
18.A role for sorting nexin 27 in AMPA receptor trafficking. Loo LS, Tang N, Al-Haddawi M, Dawe GS, Hong W. Nat Commun 5, 3176, (2014). PMID: 24458027
19.Measuring interactions of FERM domain-containing sorting Nexin proteins with endosomal lipids and cargo molecules. Ghai R, Mobli M, Collins BM. Meth. Enzymol. 534, 331-49, (2014). View articlePMID: 24359963
20.Sorting nexin 27 regulates basal and stimulated brush border trafficking of NHE3. Singh V, Yang J, Cha B, Chen TE, Sarker R, Yin J, Avula LR, Tse M, Donowitz M. Mol Biol Cell 26, 2030-43, (2015). PMID: 25851603
21.SNX27 mediates retromer tubule entry and endosome-to-plasma membrane trafficking of signalling receptors. Temkin P, Lauffer B, Jager S, Cimermancic P, Krogan NJ, von Zastrow M. Nat Cell Biol 13, 715-21, (2011). PMID: 21602791
22.Deficiency of sorting nexin 27 (SNX27) leads to growth retardation and elevated levels of N-methyl-D-aspartate receptor 2C (NR2C). Cai L, Loo LS, Atlashkin V, Hanson BJ, Hong W. Mol Cell Biol 31, 1734-47, (2011). PMID: 21300787
23.A global analysis of SNX27-retromer assembly and cargo specificity reveals a function in glucose and metal ion transport. Steinberg F, Gallon M, Winfield M, Thomas EC, Bell AJ, Heesom KJ, Tavare JM, Cullen PJ. Nat. Cell Biol. 15, 461-71, (2013). View articlePMID: 23563491
24.SNX27 mediates PDZ-directed sorting from endosomes to the plasma membrane. Lauffer BE, Melero C, Temkin P, Lei C, Hong W, Kortemme T, von Zastrow M. J. Cell Biol. 190, 565-74, (2010). View articlePMID: 20733053
25.Sorting nexin 27 interacts with the Cytohesin associated scaffolding protein (CASP) in lymphocytes. MacNeil AJ, Mansour M, Pohajdak B. Biochem Biophys Res Commun 359, 848-53, (2007). PMID: 17577583
26.Sorting nexin 27 protein regulates trafficking of a p21-activated kinase (PAK) interacting exchange factor (β-Pix)-G protein-coupled receptor kinase interacting protein (GIT) complex via a PDZ domain interaction. Valdes JL, Tang J, McDermott MI, Kuo JC, Zimmerman SP, Wincovitch SM, Waterman CM, Milgram SL, Playford MP. J Biol Chem 286, 39403-16, (2011). PMID: 21926430
27.Phox homology band 4.1/ezrin/radixin/moesin-like proteins function as molecular scaffolds that interact with cargo receptors and Ras GTPases. Ghai R, Mobli M, Norwood SJ, Bugarcic A, Teasdale RD, King GF, Collins BM. Proc. Natl. Acad. Sci. U.S.A. 108, 7763-8, (2011). View articlePMID: 21512128
28.Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins. Ghai R, Bugarcic A, Liu H, Norwood SJ, Skeldal S, Coulson EJ, Li SS, Teasdale RD, Collins BM. Proc. Natl. Acad. Sci. U.S.A. 110, E643-52, (2013). View articlePMID: 23382219
29.Sorting nexin 27 interacts with Fzd7 and mediates Wnt signalling. Sun L, Hu X, Chen W, He W, Zhang Z, Wang T. Biosci Rep 36, e00296, (2016). PMID: 26744382
30.Ras-association domain of sorting Nexin 27 is critical for regulating expression of GIRK potassium channels. Balana B, Bahima L, Bodhinathan K, Taura JJ, Taylor NM, Nettleton MY, Ciruela F, Slesinger PA. PLoS One 8, e59800, (2013). PMID: 23536889