Member database | CDD |
CDD type | domain |
Short name | STAT5_DBD |
Set | STAT_DBD |
Description
References
1.STAT5A is regulated by DNA damage via the tumor suppressor p53. Mukhopadhyay UK, Cass J, Raptis L, Craig AW, Bourdeau V, Varma S, SenGupta S, Elliott BE, Ferbeyre G. Cytokine 82, 70-9, (2016). PMID: 26876578
2.STAT6 is amplified in a subset of dedifferentiated liposarcoma. Doyle LA, Tao D, Marino-Enriquez A. Mod Pathol 27, 1231-7, (2014). PMID: 24457460
3.Inhibition of STAT5: a therapeutic option in BCR-ABL1-driven leukemia. Berger A, Sexl V, Valent P, Moriggl R. Oncotarget 5, 9564-76, (2014). PMID: 25333255
4.Identification and characterization of five transcription factors that are associated with evolutionarily conserved immune signaling pathways in the schistosome-transmitting snail Biomphalaria glabrata. Zhang SM, Coultas KA. Mol Immunol 48, 1868-81, (2011). PMID: 21696828
5.STAT5 is a key transcription factor for IL-3-mediated inhibition of RANKL-induced osteoclastogenesis. Lee J, Seong S, Kim JH, Kim K, Kim I, Jeong BC, Nam KI, Kim KK, Hennighausen L, Kim N. Sci Rep 6, 30977, (2016). PMID: 27485735
6.Three-dimensional structure of the Stat3beta homodimer bound to DNA. Becker S, Groner B, Muller CW. Nature 394, 145-51, (1998). View articlePMID: 9671298
7.The spectrum of STAT functions in mammary gland development. Hughes K, Watson CJ. JAKSTAT 1, 151-8, (2012). PMID: 24058764
8.Stat5 is critical for the development and maintenance of myeloproliferative neoplasm initiated by Nf1 deficiency. Sachs Z, Been RA, DeCoursin KJ, Nguyen HT, Mohd Hassan NA, Noble-Orcutt KE, Eckfeldt CE, Pomeroy EJ, Diaz-Flores E, Geurts JL, Diers MD, Hasz DE, Morgan KJ, MacMillan ML, Shannon KM, Largaespada DA, Wiesner SM. Haematologica 101, 1190-1199, (2016). PMID: 27418650
9.Syk kinase and Shp2 phosphatase inhibition cooperate to reduce FLT3-ITD-induced STAT5 activation and proliferation of acute myeloid leukemia. Richine BM, Virts EL, Bowling JD, Ramdas B, Mali R, Naoye R, Liu Z, Zhang ZY, Boswell HS, Kapur R, Chan RJ. Leukemia 30, 2094-2097, (2016). PMID: 27256702
10.Interleukin-3 signals through multiple isoforms of Stat5. Azam M, Erdjument-Bromage H, Kreider BL, Xia M, Quelle F, Basu R, Saris C, Tempst P, Ihle JN, Schindler C. EMBO J 14, 1402-11, (1995). PMID: 7537213
11.STAT5 induces miR-21 expression in cutaneous T cell lymphoma. Lindahl LM, Fredholm S, Joseph C, Nielsen BS, Jonson L, Willerslev-Olsen A, Gluud M, Blumel E, Petersen DL, Sibbesen N, Hu T, Nastasi C, Krejsgaard T, Jæhger D, Persson JL, Mongan N, Wasik MA, Litvinov IV, Sasseville D, Koralov SB, Bonefeld CM, Geisler C, Woetmann A, Ralfkiaer E, Iversen L, Odum N. Oncotarget 7, 45730-45744, (2016). PMID: 27329723
12.Ixodes scapularis JAK-STAT pathway regulates tick antimicrobial peptides, thereby controlling the agent of human granulocytic anaplasmosis. Liu L, Dai J, Zhao YO, Narasimhan S, Yang Y, Zhang L, Fikrig E. J Infect Dis 206, 1233-41, (2012). PMID: 22859824
13.Structure of the amino-terminal protein interaction domain of STAT-4. Vinkemeier U, Moarefi I, Darnell JE Jr, Kuriyan J. Science 279, 1048-52, (1998). View articlePMID: 9461439
14.STAT5A and STAT5B have opposite correlations with drug response gene expression. Lamba V, Jia B, Liang F. Biochem Biophys Res Commun 479, 117-124, (2016). PMID: 27264955
15.STAT5B deficiency: Impacts on human growth and immunity. Hwa V. Growth Horm IGF Res 28, 16-20, (2016). PMID: 26703237
16.Structure of the unphosphorylated STAT5a dimer. Neculai D, Neculai AM, Verrier S, Straub K, Klumpp K, Pfitzner E, Becker S. J. Biol. Chem. 280, 40782-7, (2005). View articlePMID: 16192273