Member database | CDD |
CDD type | domain |
Short name | C1_ROCK2 |
Set | C1 |
Description
References
1.RhoA/Rho-kinase in erectile tissue: mechanisms of disease and therapeutic insights. Jin L, Burnett AL. Clin Sci (Lond) 110, 153-65, (2006). PMID: 16411892
2.Molecular mechanism for the regulation of rho-kinase by dimerization and its inhibition by fasudil. Yamaguchi H, Kasa M, Amano M, Kaibuchi K, Hakoshima T. Structure 14, 589-600, (2006). View articlePMID: 16531242
3.RhoA/Rho-kinase pathway: much more than just a modulation of vascular tone. Evidence from studies in humans. Calo LA, Pessina AC. J Hypertens 25, 259-64, (2007). PMID: 17211228
4.Development of specific Rho-kinase inhibitors and their clinical application. Tamura M, Nakao H, Yoshizaki H, Shiratsuchi M, Shigyo H, Yamada H, Ozawa T, Totsuka J, Hidaka H. Biochim Biophys Acta 1754, 245-52, (2005). PMID: 16213195
5.Vascular rho kinases and their potential therapeutic applications. Budzyn K, Sobey CG. Curr Opin Drug Discov Devel 10, 590-6, (2007). PMID: 17786858
6.Rho kinase, a promising drug target for neurological disorders. Mueller BK, Mack H, Teusch N. 4, 387-98, (2005). View articlePMID: 15864268
7.Rho/Rho-kinase and C-reactive protein relationship in hypertension and atherosclerosis. Calo LA, Pagnin E, Mussap M, Davis PA, Semplicini A. Nephrol Dial Transplant 21, 1131-2, (2006). PMID: 16287911
8.Rho/Rho kinase as a potential target for the treatment of renal disease. Wakino S, Kanda T, Hayashi K. Drug News Perspect 18, 639-43, (2005). PMID: 16491166
9.The ups and downs of Rho-kinase and penile erection: upstream regulators and downstream substrates of rho-kinase and their potential role in the erectile response. Chitaley K, Webb RC, Mills TM. Int J Impot Res 15, 105-9, (2003). PMID: 12789389
10.Dependence of proliferating dedifferentiated vascular smooth muscle contraction on Rho-Rho kinase system. Nishimura J, Bi D, Kanaide H. Trends Cardiovasc Med 16, 124-8, (2006). PMID: 16713535
11.Rho kinase: a target for treating urinary bladder dysfunction? Peters SL, Schmidt M, Michel MC. Trends Pharmacol Sci 27, 492-7, (2006). PMID: 16870270
12.Development of Rho-kinase inhibitors for cardiovascular medicine. Shimokawa H, Rashid M. Trends Pharmacol Sci 28, 296-302, (2007). PMID: 17482681
13.Progress of the study of rho-kinase and future perspective of the inhibitor. Tawara S, Shimokawa H. Yakugaku Zasshi 127, 501-14, (2007). PMID: 17329936
14.Rho kinase in the regulation of cell death and survival. Shi J, Wei L. Arch Immunol Ther Exp (Warsz) 55, 61-75, (2007). PMID: 17347801
15.Rho GTPase/Rho kinase inhibition as a novel target for the treatment of glaucoma. Rao VP, Epstein DL. BioDrugs 21, 167-77, (2007). PMID: 17516712