Member database | HAMAP |
HAMAP type | family |
Short name | Phosphofructokinase_II_Long |
Description Imported from IPR011183
Diphosphate--fructose-6-phosphate 1-phosphotransferase catalyses the addition of phosphate from diphosphate (PPi) to fructose 6-phosphate to give fructose 1,6-bisphosphate (
2.7.1.90). The enzyme is also known as pyrophosphate-dependent phosphofructokinase. The usage of PPi-dependent enzymes in glycolysis presumably frees up ATP for other processes
[1].
IPR012828 represents the ATP-dependent 6-phosphofructokinase enzyme contained within Phosphofructokinase. This entry contains primarily bacterial, plant alpha, and plant beta sequences. These may be dimeric nonallosteric enzymes (bacteria) or allosteric heterotetramers (plants)
[2].
References Imported from IPR011183
1.The structure of a pyrophosphate-dependent phosphofructokinase from the Lyme disease spirochete Borrelia burgdorferi. Moore SA, Ronimus RS, Roberson RS, Morgan HW. Structure 10, 659-71, (2002). View articlePMID: 12015149
2.Structural basis of the allosteric behaviour of phosphofructokinase. Schirmer T, Evans PR. Nature 343, 140-5, (1990). View articlePMID: 2136935