MF_02080

Peptidoglycan D,D-transpeptidase FtsI [ftsI]

HAMAP entry
Member databaseHAMAP
HAMAP typefamily
Short nameFtsI_transpept

Description
Imported from IPR037532

In addition to the cytoplasmic proteins FtsZ and FtsA, a number of integral membrane proteins are required for cell division. Among these, FtsI, also called penicillin-binding protein 3 (PBP3), is involved in septum formation
[4]
. FtsI is responsible for the synthesis of septal peptidoglycan
[1]
and is also required for FtsN localization to the septum
[3, 2]
.

References
Imported from IPR037532

1.Evidence for involvement of penicillin-binding protein 3 in murein synthesis during septation but not during cell elongation. Botta GA, Park JT. J. Bacteriol. 145, 333-40, (1981). PMID: 6450748

2.FtsN, a late recruit to the septum in Escherichia coli. Addinall SG, Cao C, Lutkenhaus J. Mol. Microbiol. 25, 303-9, (1997). View articlePMID: 9282742

3.FtsI and FtsW are localized to the septum in Escherichia coli. Wang L, Khattar MK, Donachie WD, Lutkenhaus J. J. Bacteriol. 180, 2810-6, (1998). PMID: 9603865

4.Location of some proteins involved in peptidoglycan synthesis and cell division in the inner and outer membranes of Escherichia coli. Rodriguez-Tebar A, Barbas JA, Vazquez D. J. Bacteriol. 161, 243-8, (1985). PMID: 3881388

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