MF_02205

ATP-dependent DNA helicase DinG [dinG]

HAMAP entry
Member databaseHAMAP
HAMAP typefamily
Short nameDinG_proteobact

Description
Imported from IPR039000

DinG is a DNA damage-inducible protein that functions as a helicase which translocates on single-stranded DNA (ssDNA) in the 5'-3' direction
[2]
. The ATP-dependent DNA helicase activity of DinG requires divalent cations (Mg2+, Ca2+, and Mn2+) but is not observed in the presence of Zn2+
[1]
.

References
Imported from IPR039000

1.Characterization of the DNA damage-inducible helicase DinG from Escherichia coli. Voloshin ON, Vanevski F, Khil PP, Camerini-Otero RD. J. Biol. Chem. 278, 28284-93, (2003). View articlePMID: 12748189

2.The helicase DinG responds to stress due to DNA double strand breaks. Frye SA, Beyene GT, Namouchi A, Gomez-Munoz M, Homberset H, Kalayou S, Riaz T, Tonjum T, Balasingham SV. PLoS ONE 12, e0187900, (2017). View articlePMID: 29121674

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