MF_04088

Non-structural protein 1

HAMAP entry
Member databaseHAMAP
HAMAP typefamily
Short nameROTA_NSP1

Description
Imported from IPR002148

The proteins in this family are non-structural protein 1 (NSP1), also known as non-structural RNA-binding protein 53(NS53). They are RNA binding proteins that contain a characteristic cysteine rich region
[1, 2]
. They are made at low levels in infected cells and are a component of early replication and are known to accumulate on the cytoskeleton of the infected cell.

References
Imported from IPR002148

1.Comparative analysis of the rotavirus NS53 gene: conservation of basic and cysteine-rich regions in the protein and possible stem-loop structures in the RNA. Hua J, Mansell EA, Patton JT. Virology 196, 372-8, (1993). View articlePMID: 8395125

2.Structure and function of rotavirus NSP1. Taniguchi K, Kojima K, Kobayashi N, Urasawa T, Urasawa S. Arch. Virol. Suppl. 12, 53-8, (1996). PMID: 9015101

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