Member database | HAMAP |
HAMAP type | family |
Short name | ROTA_NSP1 |
Description Imported from IPR002148
The proteins in this family are non-structural protein 1 (NSP1), also known as non-structural RNA-binding protein 53(NS53). They are RNA binding proteins that contain a characteristic cysteine rich region
[1, 2]. They are made at low levels in infected cells and are a component of early replication and are known to accumulate on the cytoskeleton of the infected cell.
References Imported from IPR002148
1.Comparative analysis of the rotavirus NS53 gene: conservation of basic and cysteine-rich regions in the protein and possible stem-loop structures in the RNA. Hua J, Mansell EA, Patton JT. Virology 196, 372-8, (1993). View articlePMID: 8395125