F
IPR012170

TFIIH subunit Ssl1/p44

InterPro entry
Short nameTFIIH_SSL1/p44

Description

This entry represents Ssl1/p44m (also known as GTF2H2), which is a component of the transcription factor TFIIH core (includes XPB, p62, p52, p44, p34)
[1, 2]
. TFIIH complex is involved in nucleotide excision repair (NER) of damaged DNA and in RNA transcription by RNA polymerase II
[1, 3]
.

References

1.Reconstitution of TFIIH and requirement of its DNA helicase subunits, Rad3 and Rad25, in the incision step of nucleotide excision repair. Sung P, Guzder SN, Prakash L, Prakash S. J. Biol. Chem. 271, 10821-6, (1996). View articlePMID: 8631896

2.TFIIH: A multi-subunit complex at the cross-roads of transcription and DNA repair. Kolesnikova O, Radu L, Poterszman A. Adv Protein Chem Struct Biol 115, 21-67, (2019). PMID: 30798933

3.RNA polymerase transcription factor IIH holoenzyme from yeast. Svejstrup JQ, Feaver WJ, LaPointe J, Kornberg RD. J. Biol. Chem. 269, 28044-8, (1994). PMID: 7961739

GO terms

Cross References

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