IPR018371
Chitin-binding, type 1, conserved site
InterPro entry
Short name | Chitin-binding_1_CS |
Description
A number of plant and fungal proteins that bind N-acetylglucosamine (e.g. solanaceous lectins of tomato and potato, plant endochitinases, the wound-induced proteins: hevein, win1 and win2, and the Kluyveromyces lactis killer toxin alpha subunit) contain this domain
[1]. The domain may occur in one or more copies and is thought to be involved in recognition or binding of chitin subunits
[2, 3]. In chitinases, as well as in the potato wound-induced proteins, the 43-residue domain directly follows the signal sequence and is therefore at the N terminus of the mature protein; in the killer toxin alpha subunit it is located in the central section of the protein.
References
1.Evolution of a family of N-acetylglucosamine binding proteins containing the disulfide-rich domain of wheat germ agglutinin. Wright HT, Sandrasegaram G, Wright CS. J. Mol. Evol. 33, 283-94, (1991). View articlePMID: 1757999
2.Kluyveromyces lactis toxin has an essential chitinase activity. Butler AR, O'Donnell RW, Martin VJ, Gooday GW, Stark MJ. Eur. J. Biochem. 199, 483-8, (1991). View articlePMID: 2070799
3.The gene for stinging nettle lectin (Urtica dioica agglutinin) encodes both a lectin and a chitinase. Lerner DR, Raikhel NV. J. Biol. Chem. 267, 11085-91, (1992). View articlePMID: 1375935
GO terms
Cross References
Contributing Member Database Entry
- PROSITE patterns:PS00026