NF040815

site-specific tyrosine recombinase/integron integrase

NCBIfam entry
Member databaseNCBIfam (includes TIGRFAMs)
NCBIfam typefamily
Short namerecomb_XerA_Arch

Description

Proteins of this family are site-specific tyrosine recombinases in Archaea. The recent study (
[cite:PUB00153459]
) reported that they were the key components of archaeal integrons and were involved in cross-domain gene transfer.

References

1.Discovery of integrons in Archaea: Platforms for cross-domain gene transfer. Ghaly TM, Tetu SG, Penesyan A, Qi Q, Rajabal V, Gillings MR. Sci Adv 8, eabq6376, (2022). View articlePMID: 36383678

Further reading

2. Evidence for a Xer/dif system for chromosome resolution in archaea. Cortez D, Quevillon-Cheruel S, Gribaldo S, Desnoues N, Sezonov G, Forterre P, Serre MC. PLoS Genet. 6, e1001166, (2010). View articlePMID: 20975945

3. The carboxy-terminal αN helix of the archaeal XerA tyrosine recombinase is a molecular switch to control site-specific recombination. Serre MC, El Arnaout T, Brooks MA, Durand D, Lisboa J, Lazar N, Raynal B, van Tilbeurgh H, Quevillon-Cheruel S. PLoS ONE 8, e63010, (2013). View articlePMID: 23667562

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