TIGR00250

Holliday junction resolvase RuvX

NCBIfam entry
Member databaseNCBIfam (includes TIGRFAMs)
NCBIfam typefamily
Short nameRNAse_H_YqgF

Description

This protein family, which exhibits an RNAse H fold in crystal structure, has been proposed as a putative Holliday junction resolvase, an alternate to RuvC, but also has been proposed as a pre-16S rRNA nuclease.

References

1. Solution structure of the hypothetical protein YqgF from Escherichia coli reveals an RNAse H fold. Liu D, Wang YS, Wyss DF. J. Biomol. NMR 27, 389-92, (2003). View articlePMID: 14512736

2. Mutations in the essential Escherichia coli gene, yqgF, and their effects on transcription. Iwamoto A, Osawa A, Kawai M, Honda H, Yoshida S, Furuya N, Kato J. J. Mol. Microbiol. Biotechnol. 22, 17-23, (2012). View articlePMID: 22353788

3. SURVEY AND SUMMARY: holliday junction resolvases and related nucleases: identification of new families, phyletic distribution and evolutionary trajectories. Aravind L, Makarova KS, Koonin EV. Nucleic Acids Res. 28, 3417-32, (2000). View articlePMID: 10982859

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