TIGR01455

phosphoglucosamine mutase

NCBIfam entry
Member databaseNCBIfam (includes TIGRFAMs)
NCBIfam typefamily
Short nameglmM

Description

This HMM describes GlmM, phosphoglucosamine mutase, previous called MrsA in E. coli, UreC in Helicobacter pylori, and femR315 or FemD in Staphlococcus aureus. In bacteria, the enzyme converts glucosamine-6-phosphate to glucosamine-1-phosphate as part of the pathway toward UDP-N-acetylglucosamine for peptidoglycan and lipopolysaccharides.

References

1. The Helicobacter pylori ureC gene codes for a phosphoglucosamine mutase. De Reuse H, Labigne A, Mengin-Lecreulx D. J. Bacteriol. 179, 3488-93, (1997). View articlePMID: 9171391

2. The femR315 gene from Staphylococcus aureus, the interruption of which results in reduced methicillin resistance, encodes a phosphoglucosamine mutase. Jolly L, Wu S, van Heijenoort J, de Lencastre H, Mengin-Lecreulx D, Tomasz A. J. Bacteriol. 179, 5321-5, (1997). View articlePMID: 9286983

3. Characterization of the essential gene glmM encoding phosphoglucosamine mutase in Escherichia coli. Mengin-Lecreulx D, van Heijenoort J. J. Biol. Chem. 271, 32-9, (1996). View articlePMID: 8550580

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