Member database | NCBIfam (includes TIGRFAMs) |
NCBIfam type | family |
Short name | VI_effect_Hcp1 |
Description
TssD, originally called Hcp1 (hemolysin coregulated protein), forms hexameric ring-shaped structures that stack to form the tube of type VI secretion systems (T6SS).(
[cite:PUB00105085]
). Pathogens may have many multiple members of this family, with three to ten in Erwinia carotovora, Yersinia pestis, uropathogenic Escherichia coli, and the insect pathogen Photorhabdus luminescens.
References
Further reading
2. A virulence locus of Pseudomonas aeruginosa encodes a protein secretion apparatus. Mougous JD, Cuff ME, Raunser S, Shen A, Zhou M, Gifford CA, Goodman AL, Joachimiak G, Ordonez CL, Lory S, Walz T, Joachimiak A, Mekalanos JJ. Science 312, 1526-30, (2006). View articlePMID: 16763151
Integrated to
External Links
Representative structure
4hkh: Structure of the Hcp1 protein from E. coli EAEC 042 pathovar, mutants N93W-S158W