Member database | NCBIfam (includes TIGRFAMs) |
NCBIfam type | family |
Short name | ABC_ABC_ChvD |
Description
Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
References
1. ChvD, a chromosomally encoded ATP-binding cassette transporter-homologous protein involved in regulation of virulence gene expression in Agrobacterium tumefaciens. Liu Z, Jacobs M, Schaff DA, McCullen CA, Binns AN. J Bacteriol 183, 3310-7, (2001). PMID: 11344138