PTHR10343

CRP1/MDG1 DNA-binding & kinase subunit
AI

PANTHER entry
This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Member databasePANTHER
PANTHER typefamily
Short nameCRP1_MDG1_kinase
AI

Description

AI-generatedUnreviewed
The CRP1/MDG1 family includes proteins involved in various cellular processes. Members like Cruciform DNA-recognizing protein 1 bind to cruciform DNA and enhance its cleavage by specific endonucleases, playing a role in DNA repair and maintenance. Other members, such as the SNF1 protein kinase subunits, are integral to the SNF1 kinase complex, which adapts to glucose limitation by regulating transcription, metabolism, and development. This complex also influences cellular aging and polarity. Additionally, the family encompasses proteins like MDG1, which are involved in G-protein mediated signal transduction and the regulation of polarized cell growth in response to pheromones. The AMP-activated protein kinase subunits within the family act as energy sensors, regulating cellular energy metabolism by activating energy-producing pathways and inhibiting energy-consuming processes in response to ATP level changes.
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