PTHR10982

Fungal fatty acid synthase
AI

PANTHER entry
This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Member databasePANTHER
PANTHER typefamily
Short nameFungal_FAS
AI

Description

AI-generatedUnreviewed
The fungal fatty acid synthase (FAS) family is responsible for the biosynthesis of long-chain fatty acids, which are essential components of cell membranes and precursors for various bioactive compounds. These enzymes catalyze the formation of fatty acids from acetyl-CoA, malonyl-CoA, and NADPH. The FAS complex is typically composed of two subunits, alpha and beta, each containing multiple catalytic domains that work in concert to extend the fatty acid chain. In fungi, these enzymes are also involved in the production of secondary metabolites, such as mycotoxins and bioactive lipopeptides, by providing starter units or precursors for non-ribosomal peptide synthetases and polyketide synthases. The FAS family plays a crucial role in fungal metabolism and pathogenicity, as some of the secondary metabolites synthesized are virulence factors or have pharmacological significance.
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