PTHR11609

PurK/PurT family ATP-dependent AIR carboxylases
AI

PANTHER entry
This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Member databasePANTHER
PANTHER typefamily
Short namePurK/PurT
AI

Description

AI-generatedUnreviewed
The PurK/PurT family includes enzymes that catalyze the ATP-dependent carboxylation of 5-aminoimidazole ribonucleotide (AIR) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) using bicarbonate as a substrate. This reaction is a critical step in the de novo biosynthesis of purine nucleotides, which are essential building blocks for DNA and RNA, as well as for the regulation of energy within cells. Members of the PurK/PurT family are found across various bacterial species, reflecting the fundamental nature of purine biosynthesis in cellular metabolism and genetic information processing.
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