This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Member database | PANTHER |
PANTHER type | family |
Short name | Actin-binding_cytoskeletal_reg AI |
Description
AI-generatedUnreviewed
This family of proteins includes actin-binding proteins that play a crucial role in the organization and stabilization of the cytoskeleton. They are involved in cross-linking F-actin, thereby anchoring actin to various intracellular structures and contributing to the formation of actin networks. Some members are implicated in cytokinesis, vesicular trafficking, and tight junction assembly. Certain proteins within this family may also function as transcriptional coactivators, interacting with nuclear hormone receptors to modulate gene expression. Additionally, some are involved in the maintenance of cell shape, cellular organization, and membrane stability, particularly in erythrocytes and neuronal tissues.
External Links
Representative structure
1u5p: Crystal Structure of Repeats 15 and 16 of Chicken Brain Alpha Spectrin