PTHR12670

CERAMIDASE

PANTHER entry
Member databasePANTHER
PANTHER typefamily

Description
Imported from IPR006823

This family represents a group of neutral/alkaline ceramidases found in both bacteria and eukaryotes
[1, 2, 3]
. They hydrolyse the sphingolipid ceramide into sphingosine and free fatty acid.

References
Imported from IPR006823

1.Molecular cloning of the full-length cDNA encoding mouse neutral ceramidase. A novel but highly conserved gene family of neutral/alkaline ceramidases. Tani M, Okino N, Mori K, Tanigawa T, Izu H, Ito M. J. Biol. Chem. 275, 11229-34, (2000). View articlePMID: 10753931

2.Molecular cloning and characterization of a human mitochondrial ceramidase. El Bawab S, Roddy P, Qian T, Bielawska A, Lemasters JJ, Hannun YA. J. Biol. Chem. 275, 21508-13, (2000). View articlePMID: 10781606

3.Molecular cloning, sequencing, and expression of the gene encoding alkaline ceramidase from Pseudomonas aeruginosa. Cloning of a ceramidase homologue from Mycobacterium tuberculosis. Okino N, Ichinose S, Omori A, Imayama S, Nakamura T, Ito M. J. Biol. Chem. 274, 36616-22, (1999). View articlePMID: 10593963

This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice and Terms of Use.