Member database | PANTHER |
PANTHER type | family |
Description Imported from IPR039055
References Imported from IPR039055
1.MICU1 is an essential gatekeeper for MCU-mediated mitochondrial Ca(2+) uptake that regulates cell survival. Mallilankaraman K, Doonan P, Cardenas C, Chandramoorthy HC, Muller M, Miller R, Hoffman NE, Gandhirajan RK, Molgo J, Birnbaum MJ, Rothberg BS, Mak DO, Foskett JK, Madesh M. Cell 151, 630-44, (2012). View articlePMID: 23101630
2.The mitochondrial calcium uniporter is a multimer that can include a dominant-negative pore-forming subunit. Raffaello A, De Stefani D, Sabbadin D, Teardo E, Merli G, Picard A, Checchetto V, Moro S, Szabo I, Rizzuto R. EMBO J. 32, 2362-76, (2013). View articlePMID: 23900286
3.A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter. De Stefani D, Raffaello A, Teardo E, Szabo I, Rizzuto R. Nature 476, 336-40, (2011). View articlePMID: 21685888
4.Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter. Baughman JM, Perocchi F, Girgis HS, Plovanich M, Belcher-Timme CA, Sancak Y, Bao XR, Strittmatter L, Goldberger O, Bogorad RL, Koteliansky V, Mootha VK. Nature 476, 341-5, (2011). View articlePMID: 21685886