This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Member database | PANTHER |
PANTHER type | family |
Short name | Rap1_Ran_GAP AI |
Description
AI-generatedUnreviewed
The protein family is involved in the regulation of GTPase activity for nuclear Ras-related regulatory proteins such as Rap1, Rap2, and Ran, typically converting them to an inactive GDP-bound state. Members of the family play key roles in various cellular processes including cell cycle progression, epithelial cell morphogenesis, polarity, adhesion, cytoskeletal organization, and dendritic spine morphogenesis. They are also implicated in the regulation of cell adhesion and chemotaxis by controlling myosin II assembly and disassembly. The family contributes to the spatial and temporal regulation of these processes, which are crucial for proper cell function and development.