PTHR21231

XPA-BINDING PROTEIN 1-RELATED

PANTHER entry
Member databasePANTHER
PANTHER typefamily

Description
Imported from IPR004130

Proteins in this entry belong to the GPN-loop GTPase family
[1]
, including Npa3 (also known as Gpn1) and Gpn2/3 from budding yeasts. In humans, Npa3 homologue is known as XAB1; Gpn2 is known as GPN2/ATPBD1B; Gpn3 is known as Parcs.

References
Imported from IPR004130

1.Structural insights into a new homodimeric self-activated GTPase family. Gras S, Chaumont V, Fernandez B, Carpentier P, Charrier-Savournin F, Schmitt S, Pineau C, Flament D, Hecker A, Forterre P, Armengaud J, Housset D. EMBO Rep. 8, 569-75, (2007). View articlePMID: 17468740

Further reading

2. GTP-dependent binding and nuclear transport of RNA polymerase II by Npa3 protein. Staresincic L, Walker J, Dirac-Svejstrup AB, Mitter R, Svejstrup JQ. J. Biol. Chem. 286, 35553-61, (2011). View articlePMID: 21844196

3. Biogenesis of RNA polymerases II and III requires the conserved GPN small GTPases in Saccharomyces cerevisiae. Minaker SW, Filiatrault MC, Ben-Aroya S, Hieter P, Stirling PC. Genetics 193, 853-64, (2013). View articlePMID: 23267056

4. A role for GPN-loop GTPase yGPN1 in sister chromatid cohesion. Alonso B, Chaussinand G, Armengaud J, Godon C. Cell Cycle 10, 1828-37, (2011). PMID: 21532343

5. Eukaryotic GPN-loop GTPases paralogs use a dimeric assembly reminiscent of archeal GPN. Alonso B, Beraud C, Meguellati S, Chen SW, Pellequer JL, Armengaud J, Godon C. Cell Cycle 12, 463-72, (2013). View articlePMID: 23324351

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