This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Member database | PANTHER |
PANTHER type | family |
Short name | DNA_repair_recomb_RadA/Rad51 AI |
Description
AI-generatedUnreviewed
This family of proteins is involved in the maintenance of genomic stability through DNA repair and homologous recombination processes. Members of this family bind to single-stranded DNA and form nucleoprotein filaments, which are crucial for the homology search and strand exchange during recombination. They exhibit DNA-dependent ATPase activity and are capable of hydrolyzing ATP in a manner dependent on the presence of single-stranded DNA. These proteins are also essential for the repair of DNA damage, including double-strand breaks, and play a role in meiotic recombination, ensuring proper chromosome segregation. Some family members are specifically involved in meiotic recombination and synaptonemal complex formation, contributing to cell cycle progression during meiosis.
External Links
Representative structure
2z43: Structure of a twinned crystal of RadA