PTHR23042

Circadian Clock Transcription Factors
AI

PANTHER entry
This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Member databasePANTHER
PANTHER typefamily
Short nameCircadian_TF
AI

Description

AI-generatedUnreviewed
The protein family is involved in transcriptional regulation and forms a core component of the circadian clock, which is an internal time-keeping system that regulates physiological processes through circadian rhythms in gene expression. The family includes transcription factors that play roles in various biological processes such as angiogenesis, hematopoiesis, metabolism, cell motility, immune modulation, and response to hypoxia. Members of the family recognize specific DNA elements such as xenobiotic response elements (XRE), hypoxia response elements (HRE), and E-box elements, and they form heterodimers to activate or repress transcription. The family is also implicated in the development of the hypothalamo-pituitary axis, brain growth, visual and renal function, and cellular responses to environmental cues.
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