This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Member database | PANTHER |
PANTHER type | family |
Short name | LON-RING_domain AI |
Description
AI-generatedUnreviewed
This family of proteins includes members with a LON peptidase N-terminal domain and a RING finger motif, suggesting roles in proteolytic processing and ubiquitin-mediated pathways. The LON domain is typically associated with ATP-dependent proteases involved in the degradation of misfolded, damaged, or short-lived proteins. The RING finger domain is a zinc-binding motif often found in E3 ubiquitin ligases, which are part of the ubiquitin-proteasome system responsible for tagging proteins with ubiquitin for degradation. Some family members are known to function as transcription factors involved in cell adherence. Overall, this family appears to be involved in protein quality control, regulation of protein levels, and potentially in transcriptional regulation related to cell adhesion.