PTHR24201

Ankyrin Repeat and Cyclin-Dependent Kinase Inhibitor
AI

PANTHER entry
This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Member databasePANTHER
PANTHER typefamily
Short nameAnk_Repeat/CDKN_Inhibitor
AI

Description

AI-generatedUnreviewed
The protein family includes ankyrin repeat domain-containing proteins and cyclin-dependent kinase inhibitors. Ankyrin repeat proteins may play roles in cell division and other regulatory functions, while cyclin-dependent kinase inhibitors are involved in cell cycle regulation by interacting with CDK4 and CDK6, inhibiting cell growth and proliferation. Some family members are involved in endosomal mRNA transport, chitinase secretion, and phosphoprotein substrate recognition. Others may act as substrate-recognition components of E3 ubiquitin-protein ligase complexes, mediating ubiquitination and proteasomal degradation of target proteins.
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