This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Member database | PANTHER |
PANTHER type | family |
Short name | GPCR_Type_1 AI |
Description
AI-generatedUnreviewed
This family of proteins includes G-protein coupled receptors (GPCRs) that interact with various ligands, such as hormones, peptides, and fatty acids, to mediate diverse physiological responses. Members are involved in key biological processes including cell proliferation, migration, immune responses, and the regulation of the gonadotropic axis. These receptors typically activate phospholipase C and protein kinase C pathways or inhibit adenylyl cyclase, leading to intracellular calcium release or modulation of cyclic AMP levels. They play crucial roles in inflammation, chemotaxis, and the fine-tuning of metabolic and hormonal pathways, which are essential for normal development, immune function, and homeostasis.