PTHR24396

Transcriptional Regulators with Zinc Finger Domains
AI

PANTHER entry
This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Member databasePANTHER
PANTHER typefamily
Short nameTranscr_Reg_ZincFinger
AI

Description

AI-generatedUnreviewed
The protein family is involved in transcriptional regulation, linking histone methyltransferases to corepressor machinery and regulating gene expression in response to extracellular amino acid levels. Members are synthesized as latent cytoplasmic precursors, activated by specific sensor systems, and then translocate to the nucleus to induce expression of regulated genes. Some members contain C2H2-type zinc fingers mediating interactions with other proteins, while others have inhibitory domains for cytoplasmic retention and negative regulation of transcription.
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