PTHR32308

HpcH/HpaI aldolase
AI

PANTHER entry
This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Member databasePANTHER
PANTHER typefamily
Short nameHpcH_HpaI_aldolase
AI

Description

AI-generatedUnreviewed
The HpcH/HpaI aldolase family is involved in various metabolic pathways, including the ethylmalonyl-CoA pathway for acetate assimilation, the 3-hydroxypropionate cycle for autotrophic carbon dioxide fixation, the glyoxylate assimilation cycle, and fatty acid biosynthesis. Members of this family catalyze reversible condensation reactions involving glyoxylate with acetyl-CoA or propionyl-CoA, as well as cleavage reactions of (S)-malyl-CoA, beta-methylmalyl-CoA, and (S)-citramalyl-CoA. Some proteins also exhibit thioesterase activity, hydrolyzing (3S)-malyl-CoA to (3S)-malate and free CoA. Additionally, citrate lyase beta subunit proteins within this family function as citryl-ACP lyases. The enzymes are regulated by various factors, including divalent cations and EDTA.
This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice and Terms of Use.