PTHR33794

Extracellular Zinc Metalloprotease M4
AI

PANTHER entry
This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Member databasePANTHER
PANTHER typefamily
Short nameZinc_Metalloprotease_M4
AI

Description

AI-generatedUnreviewed
The Peptidase M4 family comprises extracellular zinc metalloproteases involved in a variety of biological processes, including pathogenesis, immune evasion, and protein activation. Members of this family have been implicated in the degradation of various substrates such as gastric mucus, elastin, collagen, and casein, which may contribute to ulcer formation, bacterial virulence, and tissue colonization. Some family members are known to cleave and activate other proteins, such as transglutaminase and cholera enterotoxin, playing roles in bacterial development and infection. The proteolytic activity of these enzymes is typically regulated by metal chelators, indicating their dependence on metal ions for function.
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