PTHR35072

COILED-COIL DOMAIN-CONTAINING PROTEIN 91

PANTHER entry
Member databasePANTHER
PANTHER typefamily

Description
Imported from IPR034592

Coiled-coil domain-containing protein 91 (also known as GGA-binding partner or accessory protein p56) colocalizes and interacts with GGA proteins, which are adaptors involved in clathrin-mediated transport between the trans-Golgi network and endosomal system
[1]
. p56 cooperates with the GGAs and clathrin in the sorting of cathepsin D to lysosomes
[2]
.

References
Imported from IPR034592

1.Binding partners for the COOH-terminal appendage domains of the GGAs and gamma-adaptin. Lui WW, Collins BM, Hirst J, Motley A, Millar C, Schu P, Owen DJ, Robinson MS. Mol. Biol. Cell 14, 2385-98, (2003). View articlePMID: 12808037

2.The trans-Golgi network accessory protein p56 promotes long-range movement of GGA/clathrin-containing transport carriers and lysosomal enzyme sorting. Mardones GA, Burgos PV, Brooks DA, Parkinson-Lawrence E, Mattera R, Bonifacino JS. Mol. Biol. Cell 18, 3486-501, (2007). View articlePMID: 17596511

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