This entry contains information that has been generated using an AI language model. Please exercise discretion when interpreting the information provided.
Member database | PANTHER |
PANTHER type | family |
Short name | RlmI_methyltransferase AI |
Description
AI-generatedUnreviewed
The RlmI family of proteins consists of ribosomal RNA large subunit methyltransferases that are responsible for the site-specific methylation of cytosine at position 1962 (m5C1962) of 23S rRNA. This modification is a post-transcriptional modification that occurs before the assembly of the 23S rRNA into the 50S ribosomal subunit. The methylation is crucial for the proper function of the ribosome, which is essential for protein synthesis. Members of the RlmI family are characterized by their membership in the broader methyltransferase superfamily, indicating a shared mechanism of action involving the transfer of a methyl group to the target cytosine residue.
External Links
Representative structure
3c0k: Crystal Structure of a ribosomal RNA methyltranferase